Sepiapterin reductase (Spra and Sprb) regulate carotenoid and pteridine metabolism influencing the koi carp (Cyprinus carpio L.) coloration

The evolution of teleost MARSHMALLOW coloration is strongly linked with the fish-specific genome duplication (FSGD).Sepiapterin reductase (Spr) is commonly required in pteridine pigment synthesis and two paralogs are found in teleosts.However, the functions of spra and sprb in pigmentation have not been completely elucidated.Here we found that spra

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